To Ruin the Repairs: Milton, Allegory, Transitional Justice

International legal theorists posit historical moments when conceptions of justice are “constituted by, and constitutive of, the transition” (Teitel). This article uses the framework of transitional justice to understand the cultural work of political allegory in the spring of 1660 on the eve of the English Restoration. Insights from transitional justice (1.) help explain how Anglican royalists convinced wary Presbyterians to assent to a restoration of the monarchy; (2.) permit a new reading of Milton’s allegory of Sin and Death in Paradise Lost; and (3.) facilitate a more critical history of the framework of transitional justice itself

Overconfidence and gender differences in wage expectations

We analyze the impact of (over-)confidence on gender differences in expected start-ing salaries using elicited beliefs of prospective university students in Germany. According to our results, female students have lower wage expectations and are less overconfident than their male counterparts. Oaxaca-Blinder decompositions of the mean show that 7.7% of the gender gap in wage expectations is attributable to a higher overconfidence of males. Decompositions of the unconditional quantiles of expected salaries suggest that the contribution of gender differences in confidence to the gender gap is particularly strong at the bottom and top of the wage expectation distribution

Exploiting Multiple Levels of Parallelism in Sparse Matrix-Matrix Multiplication

Sparse matrix-matrix multiplication (or SpGEMM) is a key primitive for many high-performance graph algorithms as well as for some linear solvers, such as algebraic multigrid. The scaling of existing parallel implementations of SpGEMM is heavily bound by communication. Even though 3D (or 2.5D) algorithms have been proposed and theoretically analyzed in the flat MPI model on Erdos-Renyi matrices, those algorithms had not been implemented in practice and their complexities had not been analyzed for the general case. In this work, we present the first ever implementation of the 3D SpGEMM formulation that also exploits multiple (intra-node and inter-node) levels of parallelism, achieving significant speedups over the state-of-the-art publicly available codes at all levels of concurrencies. We extensively evaluate our implementation and identify bottlenecks that should be subject to further research

Improving knowledge and changing behavior towards guideline based decisions in diabetes care: a controlled intervention study of a team-based learning approach for continuous professional development of physicians.

Continuing Professional Development (CPD) courses should ideally improve a physician's knowledge and change their professional behavior in daily practice towards a best clinical practice reference model and guideline adherence. Interactive methods such as team-based learning and case-based learning, as compared to lectures, can impart sustainable knowledge and lead to high satisfaction among participants. We designed an interactive case-based CPD-seminar on diabetes care using a team-based learning approach to evaluate whether it leads to an improvement of short-term knowledge and changing of behavior towards guideline based decisions and how this learning approach is perceived by participants

"Basic Principles of Sustainable Development"

This paper explores what a critical commentary on micro principles texts might look like, examining what is to be critiqued and how to do it.sustainable development, economic theory, development, environment, development policy

The Pacific Sentinel, January 2019

Editor: Jake Johnson Articles in this issue include: Happy New Years From Times Square!; First Confirmed and Evidence of Dinosaurs in Oregon; Reduced Bus Fare for Low-Income Individuals; Village Model Design Exhibit; Yellow Vest Protest of PDX; The Sentinelese and John Allen Chau; The Heat Is on the Catholic Church; Fatal Thanksgiving Encounter with CPSO; After the Sixth Day; Still Fighting for Stonewall; A Student Sails the Seas; The Statue With a Voice; Red Clocks and Rising Anti-Abortion Laws; What Is Your Face Shape?; Library Archives; Mysteries, Murder, and Mayhem in 2018; Sun Ra Rises at PAM; and 2018 in Musichttps://pdxscholar.library.pdx.edu/pacificsentinel/1018/thumbnail.jp

MesoTIRF: a novel axial super-resolution illuminator for membrane imaging over a 4.4 mm x 3.0 mm field of view

In Total Internal Reflection Fluorescence (TIRF) microscopy, a specimen is illuminated by the evanescent field produced by a beam undergoing total internal reflection, whose characteristic depth is orders of magnitude below the axial diffraction limit. The axial super-resolution and much improved contrast of TIRF gives a substantially improved signal-to-background ratio (SBR) than that which can be achieved with widefield illumination, and it is used extensively for imaging of the cell membrane [1]– [3] . Commercial TIRF objectives allow for a simple adaption to existing microscope systems. To attain a super-critical angle at the specimen plane, the illumination must enter the back focal plane of these objectives off-axis, requiring a high numerical aperture. As such, the magnification of these objectives is generally a minimum of 60x, reducing the lateral imaging field to less than 100 µm in diameter. Sub-cellular axial resolution is therefore restricted to a tiny population of cells and statistically significant data sampling may be difficult to achieve. To address this, we have developed a TIRF illuminator for the Mesolens, a custom giant objective lens with a 4x/0.47NA specification. The Mesolens provides an imaging field of 4.4 mm x 3.0 mm, and in combination with our new TIRF illuminator which we call MesoTIRF we have performed imaging of large cell populations with sub-micron resolution in three-dimensions. With MesoTIRF we demonstrate more than a 5-fold improvement in SBR and significantly reduced photobleaching rate compared to widefield epifluorescence illumination. We will present details of the MesoTIRF system together with current and emerging applications in cell imaging

Bacteria-instructed synthesis of polymers for self-selective microbial binding and labelling

The detection and inactivation of pathogenic strains of bacteria continues to be an important therapeutic goal. Hence, there is a need for materials that can bind selectively to specific microorganisms, for diagnostic or anti-infective applications, but which can be formed from simple and inexpensive building blocks. Here, we exploit bacterial redox systems to induce a copper-mediated radical polymerisation of synthetic monomers at cell surfaces, generating polymers in situ that bind strongly to the microorganisms which produced them. This ‘bacteria-instructed synthesis’ can be carried out with a variety of microbial strains, and we show that the polymers produced are self-selective binding agents for the ‘instructing’ cell types. We further expand on the bacterial redox chemistries to ‘click’ fluorescent reporters onto polymers directly at the surfaces of a range of clinical isolate strains, allowing rapid, facile and simultaneous binding and visualisation of pathogens